Chemical Research and Evaluation of the Antioxidant Activity of the Flowers of Annona coriacea Mart. (Annonaceae)

Chemical Research and Evaluation of the Antioxidant Activity of the Flowers of Annona coriacea Mart. (Annonaceae)

[ Vol. 13 , Issue. 1 ]

Author(s):

Cicera J. Camilo, Rafael P. Caldas, Sarah S. Damasceno, Cristiane M.U. Lopes, Sheyla C.X. Almeida, Jose G.M. da Costa and Fabiola F.G. Rodrigues   Pages 66 - 70 ( 5 )

Abstract:

Background: The Annona coriacea Mart. species, popularly known as "araticum", "marolo" and "araticum-liso", is distributed throughout the Cerrado in the North and Northeast of Brazil, especially in Ceará. The aim of this study is to investigate the chemical composition and evaluate the antioxidant properties of flowers of Annona coriacea.

Methods: The crude extract was obtained by maceration in 95% ethanol. A chemical screening was performed to identify classes of secondary metabolites. Quantification of flavonoids was performed by measuring the absorbance of the complex formed between the flavonoid and the aluminum color reagent. The determination of phenolic compounds was performed using the Folin-Ciocalteu reagent. The antioxidant activity was carried out from the elimination of DPPH free radicals.

Results: Chemical prospecting revealed the presence of classes of flavonoids and tannins. The quantification of flavonoids showed content of 2.17 ± 0,90 µgEqQ/g and phenols of 0.09 ± 0,01 µgEqAG/g. The antioxidant result showed IC50 value of 61.04 ± 22.10 g/mL and control with BHT of 3.16 ± 2.20 g/mL.

Conclusion: These results indicate the need for further studies involving this species aiming to obtain better information of chemical and biological properties.

Keywords:

Phytotherapy, extract, prospecting, quantification, flavonoids, phenols.

Affiliation:

Department of Chemical Biology, Laboratory of Research in Natural Products, Regional University of Cariri, Av. Cel. Antônio Luiz, 1161. Pimenta, CEP: 63105-000 Crato-CE, Brazil.

Graphical Abstract:

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